Famous for producing the Laughs stand-up comedy program on the Fox network, he is also notable for his YouTube comedy channel, which features his popular "Heckler Destroyer" videos.
Before beginning his comedy career, he earned a bachelor's degree from Columbia University.
His comedy albums include Cure for the Cable Guy (2006), The Dark Side of the Room (2008), and Steve Hofstetter's Day Off (2009). Also a radio host and journalist, he contributed to both Four Quotas and The National Lampoon Radio Sports Minute (Or So) and penned a "Stand Up Guy" column for Sports Illustrated.
He was born and raised in Queens, New York. His wife, Sara, is featured in several of his YouTube comedy videos.
He made a memorable appearance on The Late Late Show with Craig Ferguson.